BACKED BY


real science

SUPPORTING MEN's HEALTH
A HOLISTIC APPROACH

Men face unique health challenges, including higher risks of heart disease, diabetes, some cancers and mental health issues. With life expectancy in the UK being shorter for men than women, addressing preventable conditions through lifestyle changes and diet is key to overall well-being. SpanUp has been formulated with these considerations in mind, providing essential nutrients that support key areas of men's health.

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BIOAVAILABLE
brilliance

Bioavailability, which refers to how efficiently nutrients are absorbed and used by the body, is central to our ingredient selection process.

While supplement labels may indicate high nutrient dosages, the actual health impact depends on how much of those nutrients your body can access. Bioavailability is influenced by several variables, including the chemical form of the nutrient, how the supplement is manufactured, and how it is consumed (for example, whether it is taken with food, or with fat-soluble or water-soluble food or drinks).

SpanUp is formulated with bioavailability at the forefront of our minds. Here’s a comparison chart showing the bioavailability of some of the nutrients found in SpanUp and their more effective forms:

Nutrient Lower Bioavailability form High Bioavailability Form in SpanUp Benefits of Higher Bioavailability
Vitamin B12 Cyanocobalamin
Minimum 5%		 Methylcobalamin
Minimum 15%		 Better absorbed and retained in tissues
Vitamin B9 (Folate) Folic Acid
Minimum 50%		 Methylfolate (5-MTHF)
Minimum 100%		 Active form, bypasses MTHFR enzyme conversion
Zinc Zinc Sulfate
Minimum 20%		 Zinc Bisglycinate
Minimum 40%		 Better tolerance and absorption
Vitamin D Vitamin D2 (Ergocalciferol) Vitamin D3 (Cholecalciferol) More effective at raising blood levels of Vitamin D
Omega-3 (from supplements) Ethyl Ester
Minimum 20%		 Triglyceride
Minimum 50%		 Better absorbed and used by the body
Vitamin K Vitamin K1 (Phylloquinone)
Minimum 10%		 Vitamin K2 (MK-7)
Minimum 50%		 Longer half-life and better absorbed; more effective for bone & cardiovascular health

Crafted for Optimal Benefits,
supported by research

SpanUp has been crafted using the latest research, including systematic reviews and clinical trials. We’ve carefully reviewed the evidence and used expert judgment to create a formulation that’s both effective and backed by science, ensuring you get the best possible benefits from each dose.

WHY BIOAVAILABILITY AND DOSAGE,

matter for men

SpanUp is formulated with men in mind, using a science-led approach to ensure nutrients are delivered in optimal forms and dosages. Bioavailability—how efficiently nutrients are absorbed and used by the body—is central to our ingredient selection process.

We use high-quality, research-backed sources of vitamins, minerals, and botanicals, chosen for their stability, compatibility with the body, and ability to be effectively utilised. Each dosage is carefully calibrated to reflect current evidence and align with the nutritional demands of men in modern life.

By focusing on both ingredient form and quantity, SpanUp is designed to offer efficient, targeted nutritional support.

Our Ingredients